FAQs: The Study

The most comprehensive study ever on Glyphosate & Glyphosate-based herbicides

  • TOXICITY
  • CARCINOGENICITY
  • PRENATAL DEVELOPMENTAL TOXICITY
  • NEUROTOXICITY
  • MULTI-GENERATIONAL
  • ENDOCRINE DISRUPTION
  • MICROBIOME

 

The Study

The Pilot Study Results

  • Published Paper: The Need For Independent Research On The Health Effects Of Glyphosate-Based Herbicides. Environmental Health, 2018.
    Authors: Philip J Landrigan, Fiorella Belpoggi.
  • Published Paper: The Ramazzini Institute 13-Week Study On Glyphosate-Based Herbicides At Human-Equivalent Dose In Sprague Dawley Rats: Study Design And First In-Life Endpoints Evaluation. Environmental Health, 2018.
    Authors: Simona Panzacchi, Daniele Mandrioli, Fabiana Manservisi, Luciano C Bua, Laura Falcioni, Marcella Spinaci, Giovanna Galeati, Giovanni Dinelli, Rossella Miglio, Alberto Mantovani, Stefano Lorenzetti, Jianzhong Hu, Jia Chen, Melissa Perry, Philip J Landrigan, Fiorella Belpoggi.
  • Published Paper: The Ramazzini Institute 13-Week Pilot Study On Glyphosate And Roundup Administered At Human-Equivalent Dose To Sprague Dawley Rats: Effects On The Microbiome. Environmental Health, 2018.
    Authors:Qixing Mao, Fabiana Manservisi, Simona Panzacchi, Daniele Mandrioli, Ilaria Menghetti, Andrea Vornoli, Luciano C Bua, Laura Falcioni, Corina Lesseur, Jia Chen, Fiorella Belpoggi, Jianzhong Hu.

The Current Situation

  • No Real-Life Exposure Studies: There have never been any published long-term carcinogenicity or multi-generational lab studies on glyphosate at real-life exposure levels.
  • No Comprehensive Independent Study: Hundreds of studies have been carried out on glyphosate by both the pesticide industry and independent scientists using high doses over long-term periods. However, none have been both comprehensive (covering long-term toxicity, carcinogenicity and multi-generational effects) and independent of the industry that manufactures glyphosate and glyphosate herbicides.
  • Is Glyphosate an Endocrine Disruptor?: There are indications that glyphosate herbicides may be endocrine disruptors at real-life exposure levels, but there is no data that settles the question.

What data will the Ramazzini Institute global study on glyphosate provide?

This Study will be performed by scientists who are independent, at an institute that are trusted by the public. Data from the study will include:

  • Full clear long-term data on the toxicity of glyphosate and a glyphosate-based herbicide at real-life exposures
  • Full clear long-term data on the carcinogenicity of glyphosate and a glyphosate-based herbicide at real-life exposures
  • Full clear long-term data on the multi-generational effects of glyphosate and a glyphosate-based herbicide at real-life exposures
  • Full clear long-term data on the neurotoxicology effects of glyphosate and a glyphosate-based herbicide at real-life exposures
  • Full clear long-term data on the endocrine disrupting effects of glyphosate and a glyphosate-based herbicide at real-life exposures
  • Full clear long-term data on the prenatal developmental toxicity effects of glyphosate and a glyphosate-based herbicide at real-life exposures
  • Full clear long-term data on the effects of glyphosate and a glyphosate-based herbicide at real-life exposures on the microbiome

The Ramazzini Institute will supply valuable data of unprecedented power to enable regulators, governments and the general public of every country to answer the question: Are glyphosate and glyphosate-based herbicides safe at real-world levels of exposure?

The Ramazzini Institute has already started (in May 2016) a preliminary study on glyphosate and glyphosate-based herbicides, funded by 27,000 members of the public in Italy.

Why are there gaps in our knowledge regarding glyphosate?

There are many large gaps in our knowledge regarding the health effects of glyphosate and glyphosate-based herbicides, especially at real-life exposure levels of the chemical.

The main reasons for these gaps in our knowledge are:
  • Independent scientists have never had the funding available to create and carry out a comprehensive study
  • Glyphosate industry safety studies on glyphosate have never concentrated on real-life exposure levels
    of the chemical
  • Glyphosate industry safety studies on glyphosate are often ‘commercially confidential’ and kept hidden from the public and independent scientists, so cannot be independently evaluated
  • Independent researchers have never before been able to call on the expert advice of a wide range of scientific experts during the creation of the protocol for the study

The Ramazzini Institute is one of the only independent scientific bodies in the world that has the ability to create and carry out a comprehensive long-term study that will have the backing of a large number of global scientific experts as well as the general public.

Who has reviewed the Study Protocol?

Top expert scientists from the U.S. and Europe in the areas of toxicology, pesticide exposure, cancer genetics and endocrine disruption have reviewed the study protocol and given it their full support.

The Ramazzini Institute is delighted to have had cooperation on the study design from some of the most respected scientists in the world.

Budget for Study

€ 1 Million: The budget needed for each of the 5 arms of the study.

Stage 1: Carcinogenicity and Chronic Toxicity

Stage 2: Reproductive and Developmental Toxicity

Stage 3: Windows of Susceptibility

Stage 4: Microbiome and Molecular Toxicity

Stage 5: Neurotoxicity

€ 5 Million: The total budget for this study is € 5 Million.

Some parts of the study will be able to be completed with any funding amount raised from the public above € 60,000, making this our bottom limit for fund-raising.

This not-for-profit study budget is between 100% and 200% less than a similar industry or for-profit research project would be.