Are the type of rat used in the study – Sprague-Dawley rats – prone to cancer and other infections?

Sprague-Dawley rats are considered a gold-standard for toxicological and carcinogenicity bioassays and in line with current US National Toxicology Program and OECD carcinogenicity study guidelines. Sprague-Dawley rats are not particularly prone to cancer or infections, contrarily to many genetically-modified strains of rodents.